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Animal Feed

March 2, 2025 by
Animal Feed
Justin Mitchell


Zeolite clinoptilolite nanoporous feed additive for animals of veterinary importance: potentials and limitations


The research paper by Hrvoje Valpotić et al. reviews the use of clinoptilolite (CPL), a natural zeolite, as a dietary supplement in animal nutrition, particularly as an alternative to antibiotic growth promoters (AGPs). The authors discuss the increasing concern over antibiotic resistance due to the long-term use of AGPs in livestock, prompting the search for safer alternatives. CPL is highlighted for its unique properties, including detoxification, antioxidant effects, and immunostimulation, making it a promising candidate for enhancing animal health and productivity.

The review compiles scientific data on the safety and efficacy of CPL in various animal species, particularly focusing on its effects on metabolic and endocrine status, oxidative stress, and inflammatory responses in dairy cows. The authors emphasize that CPL can improve gut health, reduce the incidence of diarrhea, and enhance overall growth performance in livestock. Additionally, the article discusses the potential applications of CPL in human medicine, including its use as an adjuvant in cancer therapy and its detoxifying properties.

The authors also address the limitations of CPL, noting that while it shows promise, its effectiveness can vary based on factors such as dosage, animal species, and specific health conditions. They conclude that further research is necessary to fully understand the potential of CPL as a feed additive and its role in replacing AGPs in livestock production.

This research paper is significant in the field of veterinary medicine and animal nutrition as it addresses the urgent need for alternatives to antibiotics in livestock production. With rising concerns about antibiotic resistance, the findings on CPL provide valuable insights into how natural substances can be utilized to promote animal health without the associated risks of antibiotic use. The review contributes to ongoing discussions about sustainable farming practices and the importance of maintaining animal welfare while ensuring food safety. For readers, particularly those in veterinary and agricultural fields, the article offers a comprehensive overview of the potential benefits and limitations of using CPL, guiding future research and practical applications in animal husbandry.